Prep HPLC Column, RP C4, 10um, 100A. 21.2mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. The moderate hydrophobicity of the C4 ligand makes this stationary phase an excellent choice for purification of hydrophobic and neutral compounds while providing lower retention than C18 phases and greater retention than many C8 phases. The fully endcapped surface helps deliver reproducible separations and reliable purification performance.
68004-P21-50 is a preparative HPLC column with dimensions of 21.2 mm ID x 50 mm length, packed with 10 µm RP C4 Butyl particles featuring a 100 Å pore size. The large internal diameter is designed for high sample loading and fraction collection, while the shorter 50 mm length favors rapid purification cycles, method screening, and preparative method development. Typical flow rates are approximately 15–40 mL/min depending on system configuration, mobile phase conditions, and sample properties.
This column is intended for preparative HPLC purification where target compounds are isolated and collected for further research, development, formulation, or production. The shorter column format is particularly useful when throughput and cycle time are prioritized over maximum chromatographic resolution. Applications include pharmaceutical research, synthetic chemistry, natural product isolation, reference standard preparation, and process optimization. A specialized preparative HPLC system capable of higher flow rates, larger injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C4 Butyl stationary phase
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
Designed for preparative HPLC purification
High sample loading capacity
10 µm particles for lower operating backpressure
Suitable for higher flow rates
Less retention than C18 columns
Fast purification cycles with 50 mm column length
Excellent for process development and method scouting
Typical Applications
Preparative HPLC purification
Small molecule isolation
Pharmaceutical research
Synthetic chemistry
Natural product purification
Reference standard preparation
Process optimization
Method development
Pilot-scale purification
Fraction collection
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 21.2 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 15–40 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for purification rather than routine analytical HPLC
Used for isolation and collection of purified compounds
Offers substantially higher sample loading capacity than analytical columns
Requires a preparative HPLC system capable of higher flow rates and fraction collection
Provides less retention than C18 phases and greater retention than many C8 phases
Short column length supports fast purification and method development workflows
Special Order Item